Microbiology typhoid vaccine
Typhoid Vaccines are increasingly used by travellers to endemic areas. Here is a brief introduction to preparations available and their usage recommendations.
Heat killed phenol extracted whole cell vaccine.
a.Monovalent anti-typhoid vaccine
b.Bivalent anti-typhoid vaccine
Oral Typhoid Vaccine(Ty21a)
Live oral vaccine, a stable mutant of S.typhi strain
Typhim – Vi(ViCPS)
Contains Vi polysaccharide antigen, administered i.m or s.c
Obtained by binding Vi polysaccharide to a non-toxic recombinant protein that is identical to pseudomonas aeruginosa exotoxin A.
Ty21a and ViCPS offer comparable one year efficacy to whole cell vaccines and have lower incidence of adverse effects making them preparation of choice for travellers.
Typhoid , Vaccine Images:
Typhoid Vaccination Powerpoints:
Typhoid Vaccination Current Needs – WHO
Typhoid Fever and Current Needs
Typhoid and other Vaccinations in Pregnancy
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